nexilin (F actin binding protein)
Symbol
NEXN
(may also be known as: None)
Organism
Human
Description
This gene encodes a filamentous actin-binding protein that may function in cell adhesion and migration. Mutations in this gene have been associated with dilated cardiomyopathy, also known as CMD1CC. Alternatively spliced transcript variants have been described.[provided by RefSeq, Feb 2010]
Orthologs
| Symbol | Species | |
|---|---|---|
| nexn | Danio rerio | |
| Nexn | Mus musculus | |
| Nexn | Rattus norvegicus |
Links to external resources
Changes associated with this gene
GO Terms
| GO ID | GO Term | GO Category | |
|---|---|---|---|
| GO:0030334 | regulation of cell migration | biological_process | |
| GO:0051493 | regulation of cytoskeleton organization | biological_process | |
| GO:0005737 | cytoplasm | cellular_component | |
| GO:0005856 | cytoskeleton | cellular_component | |
| GO:0005924 | cell-substrate adherens junction | cellular_component | |
| GO:0030018 | Z disc | cellular_component | |
| GO:0030054 | cell junction | cellular_component | |
| GO:0008307 | structural constituent of muscle | molecular_function | |
| GO:0051015 | actin filament binding | molecular_function | |