urocortin 2
Symbol
UCN2
(may also be known as: None)
Organism
Human
Description
This gene is a member of the sauvagine/corticotropin-releasing factor/urotensin I family. It is structurally related to the corticotropin-releasing factor (CRF) gene and the encoded product is an endogenous ligand for CRF type 2 receptors. In the brain it may be responsible for the effects of stress on appetite. In spite of the gene family name similarity, the product of this gene has no sequence similarity to urotensin II. [provided by RefSeq, Jul 2008]
Orthologs
| Symbol | Species | |
|---|---|---|
| Ucn2 | Mus musculus | |
| Ucn2 | Rattus norvegicus |
Links to external resources
Changes associated with this gene
GO Terms
| GO ID | GO Term | GO Category | |
|---|---|---|---|
| GO:0006171 | cAMP biosynthetic process | biological_process | |
| GO:0006950 | response to stress | biological_process | |
| GO:0007586 | digestion | biological_process | |
| GO:0008283 | cell proliferation | biological_process | |
| GO:0032277 | negative regulation of gonadotropin secretion | biological_process | |
| GO:0071385 | cellular response to glucocorticoid stimulus | biological_process | |
| GO:0005576 | extracellular region | cellular_component | |
| GO:0005615 | extracellular space | cellular_component | |
| GO:0001664 | G-protein coupled receptor binding | molecular_function | |
| GO:0005102 | receptor binding | molecular_function | |
| GO:0005179 | hormone activity | molecular_function | |
| GO:0042562 | hormone binding | molecular_function | |
| GO:0051431 | corticotropin-releasing hormone receptor 2 binding | molecular_function | |