carboxypeptidase Z
Symbol
CPZ
(may also be known as: None)
Organism
Human
Description
This gene encodes a member of the metallocarboxypeptidase family. This enzyme displays carboxypeptidase activity towards substrates with basic C-terminal residues. It is most active at neutral pH and is inhibited by active site-directed inhibitors of metallocarboxypeptidases. Alternative splicing in the coding region results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Orthologs
| Symbol | Species | |
|---|---|---|
| cpz | Danio rerio | |
| Cpz | Mus musculus | |
| Cpz | Rattus norvegicus |
Links to external resources
Changes associated with this gene
GO Terms
| GO ID | GO Term | GO Category | |
|---|---|---|---|
| GO:0006508 | proteolysis | biological_process | |
| GO:0016055 | Wnt receptor signaling pathway | biological_process | |
| GO:0005576 | extracellular region | cellular_component | |
| GO:0005578 | proteinaceous extracellular matrix | cellular_component | |
| GO:0004181 | metallocarboxypeptidase activity | molecular_function | |
| GO:0008233 | peptidase activity | molecular_function | |
| GO:0008237 | metallopeptidase activity | molecular_function | |
| GO:0008270 | zinc ion binding | molecular_function | |
| GO:0046872 | metal ion binding | molecular_function | |