glyceronephosphate O-acyltransferase

Symbol

GNPAT (may also be known as: None)

Organism

Human

Description

This gene encodes an enzyme located in the peroxisomal membrane which is essential to the synthesis of ether phospholipids. Mutations in this gene are associated with rhizomelic chondrodysplasia punctata. [provided by RefSeq, Jul 2008]

Orthologs

SymbolSpecies
acl-7 Caenorhabditis elegans
Dhap-at Drosophila melanogaster
gnpat Danio rerio
Gnpat Mus musculus
Gnpat Rattus norvegicus

Links to external resources

Changes associated with this gene

Identifier Name Type Tissues Organism Gene Data Actions
DAA3490 Gene expression of GNPAT decreases with age Molecular skin Human GNPAT —

GO Terms

GO IDGO TermGO Category
GO:0007416 synapse assembly biological_process
GO:0007584 response to nutrient biological_process
GO:0008152 metabolic process biological_process
GO:0008611 ether lipid biosynthetic process biological_process
GO:0008654 phospholipid biosynthetic process biological_process
GO:0016044 cellular membrane organization biological_process
GO:0021587 cerebellum morphogenesis biological_process
GO:0030913 paranodal junction assembly biological_process
GO:0042493 response to drug biological_process
GO:0042552 myelination biological_process
GO:0042594 response to starvation biological_process
GO:0044255 cellular lipid metabolic process biological_process
GO:0044281 small molecule metabolic process biological_process
GO:0070542 response to fatty acid biological_process
GO:0005739 mitochondrion cellular_component
GO:0005777 peroxisome cellular_component
GO:0005778 peroxisomal membrane cellular_component
GO:0005782 peroxisomal matrix cellular_component
GO:0016020 membrane cellular_component
GO:0004366 glycerol-3-phosphate O-acyltransferase activity molecular_function
GO:0016287 glycerone-phosphate O-acyltransferase activity molecular_function
GO:0016290 palmitoyl-CoA hydrolase activity molecular_function
GO:0016746 transferase activity, transferring acyl groups molecular_function