Kazal-type serine peptidase inhibitor domain 1

Symbol

KAZALD1 (may also be known as: None)

Organism

Human

Description

This gene encodes a secreted member of the insulin growth factor-binding protein (IGFBP) superfamily. It contains an N-terminal insulin growth factor-binding domain, a central Kazal-type serine protease inhibitor and follistatin-like domain, and a C-terminal immunoglobulin-like domain. Studies of the mouse ortholog suggest that this gene product may have a function in bone development and bone regeneration. [provided by RefSeq, Feb 2009]

Orthologs

SymbolSpecies
kazald3 Danio rerio
Kazald1 Mus musculus
Kazald1 Rattus norvegicus

Links to external resources

Changes associated with this gene

Identifier Name Type Tissues Organism Gene Data Actions
DAA4167 Gene expression of KAZALD1 decreases with age Molecular skin Human KAZALD1 —

GO Terms

GO IDGO TermGO Category
GO:0001503 ossification biological_process
GO:0001558 regulation of cell growth biological_process
GO:0007275 multicellular organismal development biological_process
GO:0030154 cell differentiation biological_process
GO:0030198 extracellular matrix organization biological_process
GO:0005576 extracellular region cellular_component
GO:0005614 interstitial matrix cellular_component
GO:0005520 insulin-like growth factor binding molecular_function