NIMA-related kinase 11
Symbol
NEK11
(may also be known as: None)
Organism
Human
Description
This gene encodes a member of the never in mitosis gene A family of kinases. The encoded protein localizes to the nucleoli, and may function with NEK2A in the S-phase checkpoint. The encoded protein appears to play roles in DNA replication and response to genotoxic stress. Alternatively spliced transcript variants have been described.[provided by RefSeq, Mar 2009]
Orthologs
| Symbol | Species | |
|---|---|---|
| si:dkey-283f16.1 | Danio rerio | |
| Nek11 | Mus musculus | |
| Nek11 | Rattus norvegicus |
Links to external resources
Changes associated with this gene
GO Terms
| GO ID | GO Term | GO Category | |
|---|---|---|---|
| GO:0006468 | protein phosphorylation | biological_process | |
| GO:0007049 | cell cycle | biological_process | |
| GO:0007243 | intracellular protein kinase cascade | biological_process | |
| GO:0031572 | G2/M transition DNA damage checkpoint | biological_process | |
| GO:0031573 | intra-S DNA damage checkpoint | biological_process | |
| GO:0005634 | nucleus | cellular_component | |
| GO:0005730 | nucleolus | cellular_component | |
| GO:0000166 | nucleotide binding | molecular_function | |
| GO:0004674 | protein serine/threonine kinase activity | molecular_function | |
| GO:0005515 | protein binding | molecular_function | |
| GO:0005524 | ATP binding | molecular_function | |
| GO:0016772 | transferase activity, transferring phosphorus-containing groups | molecular_function | |
| GO:0046872 | metal ion binding | molecular_function | |