centromere protein M
Symbol
CENPM
(may also be known as: None)
Organism
Human
Description
The centromere is a specialized chromatin domain, present throughout the cell cycle, that acts as a platform on which the transient assembly of the kinetochore occurs during mitosis. All active centromeres are characterized by the presence of long arrays of nucleosomes in which CENPA (MIM 117139) replaces histone H3 (see MIM 601128). CENPM is an additional factor required for centromere assembly (Foltz et al., 2006 [PubMed 16622419]).[supplied by OMIM, Mar 2008]
Orthologs
| Symbol | Species | |
|---|---|---|
| cenpm | Danio rerio | |
| Cenpm | Mus musculus | |
| Cenpm | Rattus norvegicus |
Links to external resources
Changes associated with this gene
GO Terms
| GO ID | GO Term | GO Category | |
|---|---|---|---|
| GO:0000087 | M phase of mitotic cell cycle | biological_process | |
| GO:0000236 | mitotic prometaphase | biological_process | |
| GO:0000278 | mitotic cell cycle | biological_process | |
| GO:0000777 | condensed chromosome kinetochore | cellular_component | |
| GO:0005634 | nucleus | cellular_component | |
| GO:0005694 | chromosome | cellular_component | |
| GO:0005737 | cytoplasm | cellular_component | |
| GO:0005829 | cytosol | cellular_component | |