sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B


SEMA3B (may also be known as: None)




The semaphorin/collapsin family of molecules plays a critical role in the guidance of growth cones during neuronal development. The secreted protein encoded by this gene family member is important in axonal guidance and has been shown to act as a tumor suppressor by inducing apoptosis. [provided by RefSeq, Jul 2008]


si:ch211-106g4.2 Danio rerio
Sema3b Mus musculus
Sema3b Rattus norvegicus

Links to external resources

Changes associated with this gene

Identifier Name Type Tissues Organism Gene Data Actions
DAA2399 semaphorin 3B isoform 2 precursor increases with age Molecular dermis Human SEMA3B 16.1% Increase DNA Methylation
DAA2448 semaphorin 3B isoform 2 precursor increases with age Molecular mesenchymal stem cell Human SEMA3B 19.1% Increase DNA Methylation

GO Terms

GO IDGO TermGO Category
GO:0007267 cell-cell signaling biological_process
GO:0007275 multicellular organismal development biological_process
GO:0007411 axon guidance biological_process
GO:0005576 extracellular region cellular_component
GO:0005783 endoplasmic reticulum cellular_component
GO:0016020 membrane cellular_component
GO:0004872 receptor activity molecular_function