X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound
Symbol
XPNPEP2
(may also be known as: None)
Organism
Human
Description
Aminopeptidase P is a hydrolase specific for N-terminal imido bonds, which are common to several collagen degradation products, neuropeptides, vasoactive peptides, and cytokines. Structurally, the enzyme is a member of the 'pita bread fold' family and occurs in mammalian tissues in both soluble and GPI-anchored membrane-bound forms. A membrane-bound and soluble form of this enzyme have been identified as products of two separate genes. [provided by RefSeq, Jul 2008]
Orthologs
| Symbol | Species | |
|---|---|---|
| xpnpep2 | Danio rerio | |
| Xpnpep2 | Mus musculus | |
| Xpnpep2 | Rattus norvegicus | |
| FRA1 | Saccharomyces cerevisiae |
Links to external resources
Changes associated with this gene
GO Terms
| GO ID | GO Term | GO Category | |
|---|---|---|---|
| GO:0006508 | proteolysis | biological_process | |
| GO:0009987 | cellular process | biological_process | |
| GO:0005886 | plasma membrane | cellular_component | |
| GO:0016020 | membrane | cellular_component | |
| GO:0031225 | anchored to membrane | cellular_component | |
| GO:0004177 | aminopeptidase activity | molecular_function | |
| GO:0008233 | peptidase activity | molecular_function | |
| GO:0008237 | metallopeptidase activity | molecular_function | |
| GO:0016787 | hydrolase activity | molecular_function | |
| GO:0046872 | metal ion binding | molecular_function | |