tuftelin 1

Symbol

TUFT1 (may also be known as: None)

Organism

Human

Description

Tuftelin is an acidic protein that is thought to play a role in dental enamel mineralization and is implicated in caries susceptibility. It is also thought to be involved with adaptation to hypoxia, mesenchymal stem cell function, and neurotrophin nerve growth factor mediated neuronal differentiation. [provided by RefSeq, Aug 2014]

Orthologs

Symbol	Species
tuft1a	Danio rerio
Tuft1	Mus musculus
Tuft1	Rattus norvegicus

Links to external resources

Entrez Gene: 7286
OMIM: 600087
Ensembl: ENSG00000143367
UniProt: Q9NNX1
UniGene: Hs.489922
GeneCards

Changes associated with this gene

Identifier	Name	Type	Tissues	Organism	Gene	Data	Actions
DAA3449	Gene expression of TUFT1 increases with age	Molecular	skin	Human	TUFT1	—

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GO Terms

GO ID	GO Term	GO Category
GO:0030282	bone mineralization	biological_process
GO:0042476	odontogenesis	biological_process
GO:0005576	extracellular region	cellular_component
GO:0005737	cytoplasm	cellular_component
GO:0030345	structural constituent of tooth enamel	molecular_function