tropomodulin 1
Symbol
TMOD1
(may also be known as: None)
Organism
Human
Description
This gene encodes a member of the tropomodulin family. The encoded protein is an actin-capping protein that regulates tropomyosin by binding to its N-terminus, inhibiting depolymerization and elongation of the pointed end of actin filaments and thereby influencing the structure of the erythrocyte membrane skeleton. Multiple transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Oct 2009]
Orthologs
| Symbol | Species | |
|---|---|---|
| tmod1 | Danio rerio | |
| Tmod1 | Mus musculus | |
| Tmod1 | Rattus norvegicus |
Links to external resources
Changes associated with this gene
| Identifier | Name | Type | Tissues | Organism | Gene | Data | Actions |
|---|---|---|---|---|---|---|---|
| DAA2836 | Gene expression of TMOD1 increases with age | Molecular | adipose tissue | Human | TMOD1 | — |
GO Terms
| GO ID | GO Term | GO Category | |
|---|---|---|---|
| GO:0030049 | muscle filament sliding | biological_process | |
| GO:0030239 | myofibril assembly | biological_process | |
| GO:0005634 | nucleus | cellular_component | |
| GO:0005737 | cytoplasm | cellular_component | |
| GO:0005829 | cytosol | cellular_component | |
| GO:0005856 | cytoskeleton | cellular_component | |
| GO:0008180 | signalosome | cellular_component | |
| GO:0016020 | membrane | cellular_component | |
| GO:0030016 | myofibril | cellular_component | |
| GO:0030863 | cortical cytoskeleton | cellular_component | |
| GO:0003779 | actin binding | molecular_function | |
| GO:0005523 | tropomyosin binding | molecular_function | |