sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1

Symbol

SPOCK1 (may also be known as: None)

Organism

Human

Description

This gene encodes the protein core of a seminal plasma proteoglycan containing chondroitin- and heparan-sulfate chains. The protein's function is unknown, although similarity to thyropin-type cysteine protease-inhibitors suggests its function may be related to protease inhibition. [provided by RefSeq, Jul 2008]

Orthologs

SymbolSpecies
LOC100331540 Danio rerio
Spock1 Mus musculus
Spock1 Rattus norvegicus

Links to external resources

Changes associated with this gene

Identifier Name Type Tissues Organism Gene Data Actions
DAA2832 Gene expression of SPOCK1 increases with age Molecular adipose tissue Human SPOCK1 —

GO Terms

GO IDGO TermGO Category
GO:0001558 regulation of cell growth biological_process
GO:0001764 neuron migration biological_process
GO:0007155 cell adhesion biological_process
GO:0007165 signal transduction biological_process
GO:0007399 nervous system development biological_process
GO:0010812 negative regulation of cell-substrate adhesion biological_process
GO:0010951 negative regulation of endopeptidase activity biological_process
GO:0010977 negative regulation of neuron projection development biological_process
GO:0021953 central nervous system neuron differentiation biological_process
GO:0022008 neurogenesis biological_process
GO:0005576 extracellular region cellular_component
GO:0005578 proteinaceous extracellular matrix cellular_component
GO:0005615 extracellular space cellular_component
GO:0005737 cytoplasm cellular_component
GO:0014069 postsynaptic density cellular_component
GO:0016528 sarcoplasm cellular_component
GO:0031594 neuromuscular junction cellular_component
GO:0033268 node of Ranvier cellular_component
GO:0004867 serine-type endopeptidase inhibitor activity molecular_function
GO:0004869 cysteine-type endopeptidase inhibitor activity molecular_function
GO:0005509 calcium ion binding molecular_function
GO:0008191 metalloendopeptidase inhibitor activity molecular_function