mitochondrial ribosomal protein L14

Symbol

MRPL14 (may also be known as: None)

Organism

Human

Description

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. A pseudogene corresponding to this gene is found at 17p13.3. [provided by RefSeq, Jul 2008]

Orthologs

SymbolSpecies
mRpL14 Drosophila melanogaster
mrpl14 Danio rerio
Mrpl14 Mus musculus
Mrpl14 Rattus norvegicus

Links to external resources

Changes associated with this gene

GO Terms

GO IDGO TermGO Category
GO:0006412 translation biological_process
GO:0005739 mitochondrion cellular_component
GO:0005840 ribosome cellular_component
GO:0003735 structural constituent of ribosome molecular_function