chemokine (C-X3-C motif) ligand 1

Symbol

CX3CL1 (may also be known as: None)

Organism

Human

Description

Orthologs

SymbolSpecies
Cx3cl1 Mus musculus
Cx3cl1 Rattus norvegicus

Links to external resources

Changes associated with this gene

Identifier Name Type Tissues Organism Gene Data Actions
DAA2295 chemokine (C-X3-C motif) ligand 1 decreases with age Molecular temporal lobe Human CX3CL1 46.7% Decrease Gene Expression Level
DAA2298 chemokine (C-X3-C motif) ligand 1 decreases with age Molecular hippocampus Human CX3CL1 31.6% Decrease Gene Expression Level
DAA2304 chemokine (C-X3-C motif) ligand 1 decreases with age Molecular parietal lobe Human CX3CL1 61.0% Decrease Gene Expression Level
DAA2305 chemokine (C-X3-C motif) ligand 1 decreases with age Molecular parietal lobe Human CX3CL1 56.2% Decrease Gene Expression Level
DAA2307 chemokine (C-X3-C motif) ligand 1 decreases with age Molecular frontal lobe Human CX3CL1 61.1% Decrease Gene Expression Level
DAA2308 chemokine (C-X3-C motif) ligand 1 decreases with age Molecular frontal lobe Human CX3CL1 58.0% Decrease Gene Expression Level
DAA2704 Hypomethylation of CX3CL1 is positively correlated with age Molecular blood Human CX3CL1 —

Changes associated with the orthologs of this gene

Identifier Name Type Tissues Organism Gene Data Actions
DAA1856 chemokine (C-X3-C motif) ligand 1 Molecular skeletal muscle Mouse Cx3cl1 10.0% Increase Gene Expression Level
DAA1908 chemokine (C-X3-C motif) ligand 1 Molecular Anatomical System Mouse Cx3cl1 2.0% Decrease Gene Expression Level
DAA1496 chemokine (C-X3-C motif) ligand 1 Molecular kidney Mouse Cx3cl1 17.0% Increase Gene Expression Level

GO Terms

GO IDGO TermGO Category
GO:0001666 response to hypoxia biological_process
GO:0006935 chemotaxis biological_process
GO:0006952 defense response biological_process
GO:0006955 immune response biological_process
GO:0010759 positive regulation of macrophage chemotaxis biological_process
GO:0019221 cytokine-mediated signaling pathway biological_process
GO:0030168 platelet activation biological_process
GO:0030335 positive regulation of cell migration biological_process
GO:0030593 neutrophil chemotaxis biological_process
GO:0030595 leukocyte chemotaxis biological_process
GO:0032914 positive regulation of transforming growth factor beta1 production biological_process
GO:0043066 negative regulation of apoptotic process biological_process
GO:0045766 positive regulation of angiogenesis biological_process
GO:0045785 positive regulation of cell adhesion biological_process
GO:0045906 negative regulation of vasoconstriction biological_process
GO:0048247 lymphocyte chemotaxis biological_process
GO:0048661 positive regulation of smooth muscle cell proliferation biological_process
GO:0050710 negative regulation of cytokine secretion biological_process
GO:0050729 positive regulation of inflammatory response biological_process
GO:0050902 leukocyte adhesive activation biological_process
GO:0051041 positive regulation of calcium-independent cell-cell adhesion biological_process
GO:0060055 angiogenesis involved in wound healing biological_process
GO:0060080 regulation of inhibitory postsynaptic membrane potential biological_process
GO:0005576 extracellular region cellular_component
GO:0005615 extracellular space cellular_component
GO:0005625 soluble fraction cellular_component
GO:0005737 cytoplasm cellular_component
GO:0005886 plasma membrane cellular_component
GO:0009986 cell surface cellular_component
GO:0016021 integral to membrane cellular_component
GO:0042995 cell projection cellular_component
GO:0048471 perinuclear region of cytoplasm cellular_component
GO:0005102 receptor binding molecular_function
GO:0005515 protein binding molecular_function
GO:0008009 chemokine activity molecular_function