tumor necrosis factor receptor superfamily, member 17


TNFRSF17 (may also be known as: None)




The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation. [provided by RefSeq, Jul 2008]


Tnfrsf17 Mus musculus
Tnfrsf17 Rattus norvegicus

Links to external resources

Changes associated with this gene

GO Terms

GO IDGO TermGO Category
GO:0007165 signal transduction biological_process
GO:0007275 multicellular organismal development biological_process
GO:0008283 cell proliferation biological_process
GO:0033209 tumor necrosis factor-mediated signaling pathway biological_process
GO:0005886 plasma membrane cellular_component
GO:0012505 endomembrane system cellular_component
GO:0016021 integral to membrane cellular_component
GO:0004872 receptor activity molecular_function
GO:0005031 tumor necrosis factor-activated receptor activity molecular_function