pannexin 1

Symbol

Panx1 (may also be known as: AI847747)

Organism

Mouse

Orthologs

SymbolSpecies
panx1a Danio rerio
PANX1 Homo sapiens
Panx1 Rattus norvegicus

Links to external resources

Changes associated with this gene

Identifier Name Type Tissues Organism Gene Data Actions
DAA1803 pannexin 1 Molecular muscle Mouse Panx1 28.0% Increase Gene Expression Level

Changes associated with the orthologs of this gene

Identifier Name Type Tissues Organism Gene Data Actions
DAA2247 pannexin 1 decreases with age Molecular frontal lobe Human PANX1 59.9% Decrease Gene Expression Level
DAA2258 pannexin 1 decreases with age Molecular parietal lobe Human PANX1 50.0% Decrease Gene Expression Level
DAA2268 pannexin 1 decreases with age Molecular temporal lobe Human PANX1 41.6% Decrease Gene Expression Level

GO Terms

GO IDGO TermGO Category
GO:0006810 transport biological_process
GO:0006811 ion transport biological_process
GO:0006812 cation transport biological_process
GO:0006816 calcium ion transport biological_process
GO:0007267 cell-cell signaling biological_process
GO:0033198 response to ATP biological_process
GO:0034214 protein hexamerization biological_process
GO:0034220 ion transmembrane transport biological_process
GO:0050715 positive regulation of cytokine secretion biological_process
GO:0050717 positive regulation of interleukin-1 alpha secretion biological_process
GO:0050718 positive regulation of interleukin-1 beta secretion biological_process
GO:0070588 calcium ion transmembrane transport biological_process
GO:0005783 endoplasmic reticulum cellular_component
GO:0005886 plasma membrane cellular_component
GO:0005921 gap junction cellular_component
GO:0016020 membrane cellular_component
GO:0016021 integral to membrane cellular_component
GO:0030054 cell junction cellular_component
GO:0032059 bleb cellular_component
GO:0043234 protein complex cellular_component
GO:0002020 protease binding molecular_function
GO:0005102 receptor binding molecular_function
GO:0005216 ion channel activity molecular_function
GO:0005243 gap junction channel activity molecular_function
GO:0005262 calcium channel activity molecular_function
GO:0022840 leak channel activity molecular_function
GO:0044325 ion channel binding molecular_function
GO:0046982 protein heterodimerization activity molecular_function
GO:0055077 gap junction hemi-channel activity molecular_function
GO:0097110 scaffold protein binding molecular_function