protein kinase, cGMP-dependent, type II

Symbol

PRKG2 (may also be known as: None)

Organism

Human

Description

This gene encodes a protein that belongs to the serine/threonine protein kinase family of proteins. The encoded protein plays a role in the regulation of fluid balance in the intestine. A similar protein in mouse is thought to regulate differentiation and proliferation of cells in the colon. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]

Orthologs

Symbol	Species
prkg2	Danio rerio
Prkg2	Mus musculus
Prkg2	Rattus norvegicus

Links to external resources

Changes associated with this gene

Identifier	Name	Type	Tissues	Organism	Gene	Data	Actions
DAA2756	Hypomethylation of PRKG2 is positively correlated with age	Molecular	blood	Human	PRKG2	—

First
Last

GO Terms

GO ID	GO Term	GO Category
GO:0006468	protein phosphorylation	biological_process
GO:0007165	signal transduction	biological_process
GO:0007596	blood coagulation	biological_process
GO:0044281	small molecule metabolic process	biological_process
GO:0046209	nitric oxide metabolic process	biological_process
GO:0050999	regulation of nitric-oxide synthase activity	biological_process
GO:0005829	cytosol	cellular_component
GO:0000166	nucleotide binding	molecular_function
GO:0004672	protein kinase activity	molecular_function
GO:0004674	protein serine/threonine kinase activity	molecular_function
GO:0004692	cGMP-dependent protein kinase activity	molecular_function
GO:0005524	ATP binding	molecular_function
GO:0030553	cGMP binding	molecular_function
▼ Show more GO terms