protein kinase, cGMP-dependent, type II
Symbol
PRKG2
(may also be known as: None)
Organism
Human
Description
This gene encodes a protein that belongs to the serine/threonine protein kinase family of proteins. The encoded protein plays a role in the regulation of fluid balance in the intestine. A similar protein in mouse is thought to regulate differentiation and proliferation of cells in the colon. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
Orthologs
| Symbol | Species | |
|---|---|---|
| prkg2 | Danio rerio | |
| Prkg2 | Mus musculus | |
| Prkg2 | Rattus norvegicus |
Links to external resources
Changes associated with this gene
GO Terms
| GO ID | GO Term | GO Category | |
|---|---|---|---|
| GO:0006468 | protein phosphorylation | biological_process | |
| GO:0007165 | signal transduction | biological_process | |
| GO:0007596 | blood coagulation | biological_process | |
| GO:0044281 | small molecule metabolic process | biological_process | |
| GO:0046209 | nitric oxide metabolic process | biological_process | |
| GO:0050999 | regulation of nitric-oxide synthase activity | biological_process | |
| GO:0005829 | cytosol | cellular_component | |
| GO:0000166 | nucleotide binding | molecular_function | |
| GO:0004672 | protein kinase activity | molecular_function | |
| GO:0004674 | protein serine/threonine kinase activity | molecular_function | |
| GO:0004692 | cGMP-dependent protein kinase activity | molecular_function | |
| GO:0005524 | ATP binding | molecular_function | |
| GO:0030553 | cGMP binding | molecular_function | |