pleckstrin

Symbol

PLEK (may also be known as: None)

Organism

Human

Description

Orthologs

SymbolSpecies
plek Danio rerio
Plek Mus musculus
Plek Rattus norvegicus

Links to external resources

Changes associated with this gene

Identifier Name Type Tissues Organism Gene Data Actions
DAA3326 Gene expression of PLEK decreases with age Molecular skin Human PLEK —

Changes associated with the orthologs of this gene

Identifier Name Type Tissues Organism Gene Data Actions
DAA1622 pleckstrin Molecular lung Mouse Plek 13.0% Increase Gene Expression Level

GO Terms

GO IDGO TermGO Category
GO:0002244 hemopoietic progenitor cell differentiation biological_process
GO:0002576 platelet degranulation biological_process
GO:0006904 vesicle docking involved in exocytosis biological_process
GO:0007229 integrin-mediated signaling pathway biological_process
GO:0007596 blood coagulation biological_process
GO:0010572 positive regulation of platelet activation biological_process
GO:0010920 negative regulation of inositol phosphate biosynthetic process biological_process
GO:0010925 positive regulation of inositol-polyphosphate 5-phosphatase activity biological_process
GO:0030030 cell projection organization biological_process
GO:0030168 platelet activation biological_process
GO:0030836 positive regulation of actin filament depolymerization biological_process
GO:0030845 inhibition of phospholipase C activity involved in G-protein coupled receptor signaling pathway biological_process
GO:0030866 cortical actin cytoskeleton organization biological_process
GO:0031529 ruffle organization biological_process
GO:0031532 actin cytoskeleton reorganization biological_process
GO:0032233 positive regulation of actin filament bundle assembly biological_process
GO:0033625 positive regulation of integrin activation biological_process
GO:0035556 intracellular signal transduction biological_process
GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway biological_process
GO:0046488 phosphatidylinositol metabolic process biological_process
GO:0050849 negative regulation of calcium-mediated signaling biological_process
GO:0060305 regulation of cell diameter biological_process
GO:0070493 thrombin receptor signaling pathway biological_process
GO:0070527 platelet aggregation biological_process
GO:0070528 protein kinase C signaling cascade biological_process
GO:0070560 protein secretion by platelet biological_process
GO:0005576 extracellular region cellular_component
GO:0005624 membrane fraction cellular_component
GO:0005625 soluble fraction cellular_component
GO:0005737 cytoplasm cellular_component
GO:0005829 cytosol cellular_component
GO:0032587 ruffle membrane cellular_component
GO:0005080 protein kinase C binding molecular_function
GO:0005515 protein binding molecular_function
GO:0042803 protein homodimerization activity molecular_function
GO:0043325 phosphatidylinositol-3,4-bisphosphate binding molecular_function