phosphoglucomutase 3
Symbol
PGM3
(may also be known as: None)
Organism
Human
Description
This gene encodes a member of the phosphohexose mutase family. The encoded protein mediates both glycogen formation and utilization by catalyzing the interconversion of glucose-1-phosphate and glucose-6-phosphate. A non-synonymous single nucleotide polymorphism in this gene may play a role in resistance to diabetic nephropathy and neuropathy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010]
Orthologs
| Symbol | Species | |
|---|---|---|
| CELE_F21D5.1 | Caenorhabditis elegans | |
| nst | Drosophila melanogaster | |
| pgm3 | Danio rerio | |
| Pgm3 | Mus musculus | |
| Pgm3 | Rattus norvegicus | |
| PCM1 | Saccharomyces cerevisiae | |
| SPAC1296.01c | Schizosaccharomyces pombe |
Links to external resources
Changes associated with this gene
| Identifier | Name | Type | Tissues | Organism | Gene | Data | Actions |
|---|---|---|---|---|---|---|---|
| DAA2824 | Gene expression of PGM3 decreases with age | Molecular | adipose tissue | Human | PGM3 | — |
GO Terms
| GO ID | GO Term | GO Category | |
|---|---|---|---|
| GO:0005975 | carbohydrate metabolic process | biological_process | |
| GO:0006041 | glucosamine metabolic process | biological_process | |
| GO:0006048 | UDP-N-acetylglucosamine biosynthetic process | biological_process | |
| GO:0006488 | dolichol-linked oligosaccharide biosynthetic process | biological_process | |
| GO:0007283 | spermatogenesis | biological_process | |
| GO:0009790 | embryo development | biological_process | |
| GO:0009792 | embryo development ending in birth or egg hatching | biological_process | |
| GO:0018279 | protein N-linked glycosylation via asparagine | biological_process | |
| GO:0019255 | glucose 1-phosphate metabolic process | biological_process | |
| GO:0030097 | hemopoiesis | biological_process | |
| GO:0043687 | post-translational protein modification | biological_process | |
| GO:0044267 | cellular protein metabolic process | biological_process | |
| GO:0005575 | cellular_component | cellular_component | |
| GO:0005829 | cytosol | cellular_component | |
| GO:0000287 | magnesium ion binding | molecular_function | |
| GO:0004610 | phosphoacetylglucosamine mutase activity | molecular_function | |
| GO:0004614 | phosphoglucomutase activity | molecular_function | |
| GO:0016853 | isomerase activity | molecular_function | |