serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5

Symbol

SERPINA5 (may also be known as: PAI3, PROC)

Organism

Human

Orthologs

SymbolSpecies
Serpina5 Mus musculus
Serpina5 Rattus norvegicus

Links to external resources

Changes associated with this gene

Identifier Name Type Tissues Organism Gene Data Actions
DAA3310 Gene expression of SERPINA5 decreases with age Molecular skin Human SERPINA5 —
DAA282 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 Molecular kidney Human SERPINA5 11.0% Decrease Gene Expression Level

GO Terms

GO IDGO TermGO Category
GO:0006810 transport biological_process
GO:0006869 lipid transport biological_process
GO:0007283 spermatogenesis biological_process
GO:0007342 fusion of sperm to egg plasma membrane biological_process
GO:0010951 negative regulation of endopeptidase activity biological_process
GO:0030162 regulation of proteolysis biological_process
GO:0045861 negative regulation of proteolysis biological_process
GO:0002080 acrosomal membrane cellular_component
GO:0005576 extracellular region cellular_component
GO:0005615 extracellular space cellular_component
GO:0009897 external side of plasma membrane cellular_component
GO:0016020 membrane cellular_component
GO:0031091 platelet alpha granule cellular_component
GO:0031094 platelet dense tubular network cellular_component
GO:0036024 protein C inhibitor-TMPRSS7 complex cellular_component
GO:0036025 protein C inhibitor-TMPRSS11E complex cellular_component
GO:0036026 protein C inhibitor-PLAT complex cellular_component
GO:0036027 protein C inhibitor-PLAU complex cellular_component
GO:0036028 protein C inhibitor-thrombin complex cellular_component
GO:0036029 protein C inhibitor-KLK3 complex cellular_component
GO:0036030 protein C inhibitor-plasma kallikrein complex cellular_component
GO:0043234 protein complex cellular_component
GO:0097181 protein C inhibitor-coagulation factor V complex cellular_component
GO:0097182 protein C inhibitor-coagulation factor Xa complex cellular_component
GO:0097183 protein C inhibitor-coagulation factor XI complex cellular_component
GO:0001972 retinoic acid binding molecular_function
GO:0002020 protease binding molecular_function
GO:0004867 serine-type endopeptidase inhibitor activity molecular_function
GO:0005539 glycosaminoglycan binding molecular_function
GO:0008201 heparin binding molecular_function
GO:0030414 peptidase inhibitor activity molecular_function
GO:0031210 phosphatidylcholine binding molecular_function
GO:0032190 acrosin binding molecular_function