NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa
Symbol
NDUFB2
(may also be known as: None)
Organism
Human
Description
The protein encoded by this gene is a subunit of the multisubunit NADH:ubiquinone oxidoreductase (complex I). Mammalian complex I is composed of 45 different subunits. This protein has NADH dehydrogenase activity and oxidoreductase activity. It plays a important role in transfering electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Hydropathy analysis revealed that this subunit and 4 other subunits have an overall hydrophilic pattern, even though they are found within the hydrophobic protein (HP) fraction of complex I. [provided by RefSeq, Jul 2008]
Orthologs
| Symbol | Species | |
|---|---|---|
| zgc:73329 | Danio rerio | |
| Ndufb2 | Mus musculus | |
| Ndufb2 | Rattus norvegicus |
Links to external resources
Changes associated with this gene
GO Terms
| GO ID | GO Term | GO Category | |
|---|---|---|---|
| GO:0006120 | mitochondrial electron transport, NADH to ubiquinone | biological_process | |
| GO:0006810 | transport | biological_process | |
| GO:0022904 | respiratory electron transport chain | biological_process | |
| GO:0044281 | small molecule metabolic process | biological_process | |
| GO:0005739 | mitochondrion | cellular_component | |
| GO:0005743 | mitochondrial inner membrane | cellular_component | |
| GO:0005747 | mitochondrial respiratory chain complex I | cellular_component | |
| GO:0016020 | membrane | cellular_component | |
| GO:0070469 | respiratory chain | cellular_component | |
| GO:0008137 | NADH dehydrogenase (ubiquinone) activity | molecular_function | |