lectin, galactoside-binding, soluble, 1

Symbol

LGALS1 (may also be known as: None)

Organism

Human

Description

The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. This gene product may act as an autocrine negative growth factor that regulates cell proliferation. [provided by RefSeq, Jul 2008]

Orthologs

SymbolSpecies
lec-6 Caenorhabditis elegans
lgals2a Danio rerio
Lgals1 Mus musculus
Lgals1 Rattus norvegicus

Links to external resources

Changes associated with this gene

Identifier Name Type Tissues Organism Gene Data Actions
DAA3245 Gene expression of LGALS1 decreases with age Molecular skin Human LGALS1 —

GO Terms

GO IDGO TermGO Category
GO:0006915 apoptotic process biological_process
GO:0007165 signal transduction biological_process
GO:0010812 negative regulation of cell-substrate adhesion biological_process
GO:0010977 negative regulation of neuron projection development biological_process
GO:0033555 multicellular organismal response to stress biological_process
GO:0034120 positive regulation of erythrocyte aggregation biological_process
GO:0042493 response to drug biological_process
GO:0042981 regulation of apoptotic process biological_process
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB cascade biological_process
GO:0045445 myoblast differentiation biological_process
GO:0048678 response to axon injury biological_process
GO:0071333 cellular response to glucose stimulus biological_process
GO:0071407 cellular response to organic cyclic compound biological_process
GO:0005576 extracellular region cellular_component
GO:0005578 proteinaceous extracellular matrix cellular_component
GO:0005615 extracellular space cellular_component
GO:0005622 intracellular cellular_component
GO:0005634 nucleus cellular_component
GO:0005737 cytoplasm cellular_component
GO:0009986 cell surface cellular_component
GO:0031012 extracellular matrix cellular_component
GO:0001948 glycoprotein binding molecular_function
GO:0004871 signal transducer activity molecular_function
GO:0005529 sugar binding molecular_function
GO:0016936 galactoside binding molecular_function
GO:0030395 lactose binding molecular_function
GO:0042803 protein homodimerization activity molecular_function
GO:0043236 laminin binding molecular_function