stathmin 1

Symbol

STMN1 (may also be known as: None)

Organism

Human

Description

This gene belongs to the stathmin family of genes. It encodes a ubiquitous cytosolic phosphoprotein proposed to function as an intracellular relay integrating regulatory signals of the cellular environment. The encoded protein is involved in the regulation of the microtubule filament system by destabilizing microtubules. It prevents assembly and promotes disassembly of microtubules. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2009]

Orthologs

SymbolSpecies
stmn1a Danio rerio
Stmn1 Mus musculus
Stmn1 Rattus norvegicus

Links to external resources

Changes associated with this gene

Identifier Name Type Tissues Organism Gene Data Actions
DAA3242 Gene expression of STMN1 decreases with age Molecular skin Human STMN1 —

Changes associated with the orthologs of this gene

Identifier Name Type Tissues Organism Gene Data Actions
DAA1708 stathmin 1 Molecular lung Mouse Stmn1 4.0% Decrease Gene Expression Level

GO Terms

GO IDGO TermGO Category
GO:0007019 microtubule depolymerization biological_process
GO:0007052 mitotic spindle organization biological_process
GO:0007165 signal transduction biological_process
GO:0007275 multicellular organismal development biological_process
GO:0007399 nervous system development biological_process
GO:0007409 axonogenesis biological_process
GO:0009615 response to virus biological_process
GO:0030154 cell differentiation biological_process
GO:0031115 negative regulation of microtubule polymerization biological_process
GO:0035556 intracellular signal transduction biological_process
GO:0051272 positive regulation of cellular component movement biological_process
GO:0005622 intracellular cellular_component
GO:0005624 membrane fraction cellular_component
GO:0005737 cytoplasm cellular_component
GO:0005829 cytosol cellular_component
GO:0005856 cytoskeleton cellular_component
GO:0005874 microtubule cellular_component
GO:0004871 signal transducer activity molecular_function
GO:0015631 tubulin binding molecular_function