potassium inwardly-rectifying channel, subfamily J, member 8

Symbol

KCNJ8 (may also be known as: None)

Organism

Human

Description

Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins. Defects in this gene may be a cause of J-wave syndromes and sudden infant death syndrome (SIDS). [provided by RefSeq, May 2012]

Orthologs

SymbolSpecies
kcnj8 Danio rerio
Kcnj8 Mus musculus
Kcnj8 Rattus norvegicus

Links to external resources

Changes associated with this gene

Identifier Name Type Tissues Organism Gene Data Actions
DAA2616 Hypomethylation of KCNJ8 is positively correlated with age Molecular blood Human KCNJ8 —

GO Terms

GO IDGO TermGO Category
GO:0001822 kidney development biological_process
GO:0006811 ion transport biological_process
GO:0006813 potassium ion transport biological_process
GO:0007268 synaptic transmission biological_process
GO:0007507 heart development biological_process
GO:0009268 response to pH biological_process
GO:0010107 potassium ion import biological_process
GO:0032496 response to lipopolysaccharide biological_process
GO:0042311 vasodilation biological_process
GO:0043330 response to exogenous dsRNA biological_process
GO:0051607 defense response to virus biological_process
GO:0005624 membrane fraction cellular_component
GO:0005739 mitochondrion cellular_component
GO:0005792 microsome cellular_component
GO:0005886 plasma membrane cellular_component
GO:0008076 voltage-gated potassium channel complex cellular_component
GO:0008282 ATP-sensitive potassium channel complex cellular_component
GO:0016020 membrane cellular_component
GO:0016021 integral to membrane cellular_component
GO:0030016 myofibril cellular_component
GO:0042383 sarcolemma cellular_component
GO:0005242 inward rectifier potassium channel activity molecular_function
GO:0005244 voltage-gated ion channel activity molecular_function
GO:0005524 ATP binding molecular_function
GO:0015272 ATP-activated inward rectifier potassium channel activity molecular_function