homeobox B7

Symbol

HOXB7 (may also be known as: None)

Organism

Human

Description

This gene is a member of the Antp homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded nuclear protein functions as a sequence-specific transcription factor that is involved in cell proliferation and differentiation. Increased expression of this gene is associated with some cases of melanoma and ovarian carcinoma. [provided by RefSeq, Jul 2008]

Orthologs

SymbolSpecies
lbe Drosophila melanogaster
hoxb7a Danio rerio
Hoxb7 Mus musculus
Hoxb7 Rattus norvegicus

Links to external resources

Changes associated with this gene

GO Terms

GO IDGO TermGO Category
GO:0006355 regulation of transcription, DNA-dependent biological_process
GO:0007275 multicellular organismal development biological_process
GO:0009952 anterior/posterior pattern specification biological_process
GO:0030099 myeloid cell differentiation biological_process
GO:0048704 embryonic skeletal system morphogenesis biological_process
GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis biological_process
GO:0005634 nucleus cellular_component
GO:0003677 DNA binding molecular_function
GO:0003700 sequence-specific DNA binding transcription factor activity molecular_function
GO:0005515 protein binding molecular_function
GO:0043565 sequence-specific DNA binding molecular_function