homeobox A9

Symbol

HOXA9 (may also be known as: None)

Organism

Human

Description

In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. This gene is highly similar to the abdominal-B (Abd-B) gene of Drosophila. A specific translocation event which causes a fusion between this gene and the NUP98 gene has been associated with myeloid leukemogenesis. Read-through transcription exists between this gene and the upstream homeobox A10 (HOXA10) gene.[provided by RefSeq, Mar 2011]

Orthologs

SymbolSpecies
Hoxa9 Mus musculus
Hoxa9 Rattus norvegicus

Links to external resources

Changes associated with this gene

Identifier Name Type Tissues Organism Gene Data Actions
DAA3181 Gene expression of HOXA9 increases with age Molecular skin Human HOXA9 —

GO Terms

GO IDGO TermGO Category
GO:0006351 transcription, DNA-dependent biological_process
GO:0007275 multicellular organismal development biological_process
GO:0009952 anterior/posterior pattern specification biological_process
GO:0009954 proximal/distal pattern formation biological_process
GO:0030879 mammary gland development biological_process
GO:0035115 embryonic forelimb morphogenesis biological_process
GO:0048706 embryonic skeletal system development biological_process
GO:0060216 definitive hemopoiesis biological_process
GO:0005634 nucleus cellular_component
GO:0005667 transcription factor complex cellular_component
GO:0005737 cytoplasm cellular_component
GO:0003700 sequence-specific DNA binding transcription factor activity molecular_function
GO:0005515 protein binding molecular_function
GO:0043565 sequence-specific DNA binding molecular_function