histone cluster 1, H2bd
Symbol
HIST1H2BD
(may also be known as: None)
Organism
Human
Description
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H2B family. Two transcripts that encode the same protein have been identified for this gene, which is found in the large histone gene cluster on chromosome 6p22-p21.3. [provided by RefSeq, Jul 2008]
Orthologs
| Symbol | Species | |
|---|---|---|
| Hist1h2bm | Mus musculus | |
| Hist1h2bd | Rattus norvegicus |
Links to external resources
Changes associated with this gene
| Identifier | Name | Type | Tissues | Organism | Gene | Data | Actions |
|---|---|---|---|---|---|---|---|
| DAA3170 | Gene expression of HIST1H2BD decreases with age | Molecular | skin | Human | HIST1H2BD | — | |
| DAA2804 | Gene expression of HIST1H2BD decreases with age | Molecular | adipose tissue | Human | HIST1H2BD | — |
GO Terms
| GO ID | GO Term | GO Category |
|---|---|---|
| GO:0006334 | nucleosome assembly | biological_process |
| GO:0000786 | nucleosome | cellular_component |
| GO:0005634 | nucleus | cellular_component |
| GO:0005694 | chromosome | cellular_component |
| GO:0003677 | DNA binding | molecular_function |