HIV-1 Tat specific factor 1
Symbol
HTATSF1
(may also be known as: None)
Organism
Human
Description
The protein encoded by this gene functions as a cofactor for the stimulation of transcriptional elongation by HIV-1 Tat, which binds to the HIV-1 promoter through Tat-TAR interaction. This protein may also serve as a dual-function factor to couple transcription and splicing and to facilitate their reciprocal activation. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Sep 2009]
Orthologs
| Symbol | Species | |
|---|---|---|
| htatsf1 | Danio rerio | |
| Htatsf1 | Mus musculus | |
| Htatsf1 | Rattus norvegicus |
Links to external resources
Changes associated with this gene
| Identifier | Name | Type | Tissues | Organism | Gene | Data | Actions |
|---|---|---|---|---|---|---|---|
| DAA2887 | Gene expression of HTATSF1 increases with age | Molecular | adipose tissue | Human | HTATSF1 | — |
GO Terms
| GO ID | GO Term | GO Category | |
|---|---|---|---|
| GO:0006357 | regulation of transcription from RNA polymerase II promoter | biological_process | |
| GO:0019079 | viral genome replication | biological_process | |
| GO:0032784 | regulation of transcription elongation, DNA-dependent | biological_process | |
| GO:0005634 | nucleus | cellular_component | |
| GO:0005730 | nucleolus | cellular_component | |
| GO:0000166 | nucleotide binding | molecular_function | |
| GO:0003676 | nucleic acid binding | molecular_function | |
| GO:0003723 | RNA binding | molecular_function | |