F-box and leucine-rich repeat protein 6

Symbol

FBXL6 (may also be known as: None)

Organism

Human

Description

This gene encodes a member of a family of proteins that are characterized by an F-box motif. The encoded protein also contains leucine-rich repeats. F-box-containing proteins comprise one of the subunits of the SCF (SKP1-cullin-F-box) complex, which functions in phosphorylation-dependent ubiquitination. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

Orthologs

SymbolSpecies
fbl6 Drosophila melanogaster
uncharacterized_F1R3 Danio rerio
Fbxl6 Mus musculus
Fbxl6 Rattus norvegicus

Links to external resources

Changes associated with this gene

Identifier Name Type Tissues Organism Gene Data Actions
DAA2673 Hypermethylation of FBXL6 is positively correlated with age Molecular blood Human FBXL6 —

GO Terms

GO IDGO TermGO Category
GO:0006508 proteolysis biological_process
GO:0016567 protein ubiquitination biological_process
GO:0004842 ubiquitin-protein ligase activity molecular_function