growth arrest-specific 6

Symbol

GAS6 (may also be known as: None)

Organism

Human

Description

This gene product is a gamma-carboxyglutamic acid (Gla)-containing protein thought to be involved in the stimulation of cell proliferation, and may play a role in thrombosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2009]

Orthologs

SymbolSpecies
gas6 Danio rerio
Gas6 Mus musculus
Gas6 Rattus norvegicus

Links to external resources

Changes associated with this gene

Identifier Name Type Tissues Organism Gene Data Actions
DAA3144 Gene expression of GAS6 increases with age Molecular skin Human GAS6 —

GO Terms

GO IDGO TermGO Category
GO:0001764 neuron migration biological_process
GO:0002576 platelet degranulation biological_process
GO:0006508 proteolysis biological_process
GO:0007165 signal transduction biological_process
GO:0007167 enzyme linked receptor protein signaling pathway biological_process
GO:0007596 blood coagulation biological_process
GO:0008283 cell proliferation biological_process
GO:0009267 cellular response to starvation biological_process
GO:0010934 macrophage cytokine production biological_process
GO:0017187 peptidyl-glutamic acid carboxylation biological_process
GO:0030168 platelet activation biological_process
GO:0031589 cell-substrate adhesion biological_process
GO:0040008 regulation of growth biological_process
GO:0043066 negative regulation of apoptotic process biological_process
GO:0043277 apoptotic cell clearance biological_process
GO:0043491 protein kinase B signaling cascade biological_process
GO:0043687 post-translational protein modification biological_process
GO:0044267 cellular protein metabolic process biological_process
GO:0048146 positive regulation of fibroblast proliferation biological_process
GO:0050900 leukocyte migration biological_process
GO:0070374 positive regulation of ERK1 and ERK2 cascade biological_process
GO:0071363 cellular response to growth factor stimulus biological_process
GO:0005576 extracellular region cellular_component
GO:0005615 extracellular space cellular_component
GO:0005788 endoplasmic reticulum lumen cellular_component
GO:0005796 Golgi lumen cellular_component
GO:0031093 platelet alpha granule lumen cellular_component
GO:0005102 receptor binding molecular_function
GO:0005509 calcium ion binding molecular_function
GO:0030971 receptor tyrosine kinase binding molecular_function
GO:0048018 receptor agonist activity molecular_function