NADH dehydrogenase (ubiquinone) complex I, assembly factor 3

Symbol

NDUFAF3 (may also be known as: None)

Organism

Human

Description

This gene encodes a mitochondrial complex I assembly protein that interacts with complex I subunits. Mutations in this gene cause mitochondrial complex I deficiency, a fatal neonatal disorder of the oxidative phosphorylation system. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2009]

Orthologs

SymbolSpecies
CG5569 Drosophila melanogaster
ndufaf3 Danio rerio
Ndufaf3 Mus musculus
Ndufaf3 Rattus norvegicus

Links to external resources

Changes associated with this gene

Identifier Name Type Tissues Organism Gene Data Actions
DAA3765 Gene expression of NDUFAF3 decreases with age Molecular skin Human NDUFAF3 —

GO Terms

GO IDGO TermGO Category
GO:0032981 mitochondrial respiratory chain complex I assembly biological_process
GO:0005634 nucleus cellular_component
GO:0005739 mitochondrion cellular_component
GO:0005743 mitochondrial inner membrane cellular_component
GO:0016020 membrane cellular_component
GO:0005515 protein binding molecular_function