peptidyl arginine deiminase, type IV

Symbol

PADI4 (may also be known as: None)

Organism

Human

Description

This gene is a member of a gene family which encodes enzymes responsible for the conversion of arginine residues to citrulline residues. This gene may play a role in granulocyte and macrophage development leading to inflammation and immune response. [provided by RefSeq, Jul 2008]

Orthologs

SymbolSpecies
Padi4 Mus musculus
Padi4 Rattus norvegicus

Links to external resources

Changes associated with this gene

GO Terms

GO IDGO TermGO Category
GO:0006355 regulation of transcription, DNA-dependent biological_process
GO:0006464 protein modification process biological_process
GO:0016568 chromatin modification biological_process
GO:0018101 peptidyl-citrulline biosynthetic process from peptidyl-arginine biological_process
GO:0005634 nucleus cellular_component
GO:0005737 cytoplasm cellular_component
GO:0004668 protein-arginine deiminase activity molecular_function
GO:0005509 calcium ion binding molecular_function
GO:0016787 hydrolase activity molecular_function