fms-related tyrosine kinase 4

Symbol

FLT4 (may also be known as: None)

Organism

Human

Description

This gene encodes a tyrosine kinase receptor for vascular endothelial growth factors C and D. The protein is thought to be involved in lymphangiogenesis and maintenance of the lymphatic endothelium. Mutations in this gene cause hereditary lymphedema type IA. [provided by RefSeq, Jul 2008]

Orthologs

SymbolSpecies
ver-1 Caenorhabditis elegans
flt4 Danio rerio
Flt4 Mus musculus
Flt4 Rattus norvegicus

Links to external resources

Changes associated with this gene

GO Terms

GO IDGO TermGO Category
GO:0001934 positive regulation of protein phosphorylation biological_process
GO:0001938 positive regulation of endothelial cell proliferation biological_process
GO:0001944 vasculature development biological_process
GO:0001945 lymph vessel development biological_process
GO:0001946 lymphangiogenesis biological_process
GO:0002040 sprouting angiogenesis biological_process
Show more GO terms