Fc fragment of IgG, high affinity Ia, receptor (CD64)
Symbol
FCGR1A
(may also be known as: None)
Organism
Human
Description
This gene encodes a protein that plays an important role in the immune response. This protein is a high-affinity Fc-gamma receptor. The gene is one of three related gene family members located on chromosome 1. [provided by RefSeq, Jul 2008]
Orthologs
| Symbol | Species | |
|---|---|---|
| Fcgr1 | Mus musculus |
Links to external resources
Changes associated with this gene
| Identifier | Name | Type | Tissues | Organism | Gene | Data | Actions |
|---|---|---|---|---|---|---|---|
| DAA2138 | Fc fragment of IgG, high affinity Ia, receptor (CD64) increases with age | Molecular | temporal lobe | Human | FCGR1A | 151.0% Increase Gene Expression Level | |
| DAA2140 | Fc fragment of IgG, high affinity Ia, receptor (CD64) increases with age | Molecular | hippocampus | Human | FCGR1A | 423.1% Increase Gene Expression Level | |
| DAA2142 | Fc fragment of IgG, high affinity Ia, receptor (CD64) increases with age | Molecular | parietal lobe | Human | FCGR1A | 207.6% Increase Gene Expression Level | |
| DAA2144 | Fc fragment of IgG, high affinity Ia, receptor (CD64) increases with age | Molecular | frontal lobe | Human | FCGR1A | 157.3% Increase Gene Expression Level |
GO Terms
| GO ID | GO Term | GO Category | |
|---|---|---|---|
| GO:0002474 | antigen processing and presentation of peptide antigen via MHC class I | biological_process | |
| GO:0002479 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent | biological_process | |
| GO:0006911 | phagocytosis, engulfment | biological_process | |
| GO:0006955 | immune response | biological_process | |
| GO:0007165 | signal transduction | biological_process | |
| GO:0019221 | cytokine-mediated signaling pathway | biological_process | |
| GO:0042590 | antigen processing and presentation of exogenous peptide antigen via MHC class I | biological_process | |
| GO:0045087 | innate immune response | biological_process | |
| GO:0060333 | interferon-gamma-mediated signaling pathway | biological_process | |
| GO:0005886 | plasma membrane | cellular_component | |
| GO:0016021 | integral to membrane | cellular_component | |
| GO:0030669 | clathrin-coated endocytic vesicle membrane | cellular_component | |
| GO:0031901 | early endosome membrane | cellular_component | |
| GO:0004872 | receptor activity | molecular_function | |
| GO:0005057 | receptor signaling protein activity | molecular_function | |
| GO:0005515 | protein binding | molecular_function | |
| GO:0019864 | IgG binding | molecular_function | |