trypsin domain containing 1
Symbol
TYSND1
(may also be known as: None)
Organism
Human
Description
This gene encodes a protease that removes the N-terminal peroxisomal targeting signal (PTS2) from proteins produced in the cytosol, thereby facilitating their import into the peroxisome. The encoded protein is also capable of removing the C-terminal peroxisomal targeting signal (PTS1) from proteins in the peroxisomal matrix. The full-length protein undergoes self-cleavage to produce shorter, potentially inactive, peptides. Alternative splicing results in multiple transcript variants for this gene. [provided by RefSeq, Jan 2013]
Orthologs
Symbol | Species | |
---|---|---|
CG3589 | Drosophila melanogaster | |
tysnd1 | Danio rerio | |
Tysnd1 | Mus musculus | |
Tysnd1 | Rattus norvegicus |
Links to external resources
Changes associated with this gene
Identifier | Name | Type | Tissues | Organism | Gene | Data | Actions |
---|---|---|---|---|---|---|---|
DAA2955 | Gene expression of TYSND1 decreases with age | Molecular | adipose tissue | Human | TYSND1 | — |
GO Terms
GO ID | GO Term | GO Category | |
---|---|---|---|
GO:0006508 | proteolysis | biological_process | |
GO:0016485 | protein processing | biological_process | |
GO:0031998 | regulation of fatty acid beta-oxidation | biological_process | |
GO:0051260 | protein homooligomerization | biological_process | |
GO:0005777 | peroxisome | cellular_component | |
GO:0002020 | protease binding | molecular_function | |
GO:0004252 | serine-type endopeptidase activity | molecular_function | |
GO:0008233 | peptidase activity | molecular_function | |
GO:0042802 | identical protein binding | molecular_function | |