trypsin domain containing 1

Symbol

TYSND1 (may also be known as: None)

Organism

Human

Description

This gene encodes a protease that removes the N-terminal peroxisomal targeting signal (PTS2) from proteins produced in the cytosol, thereby facilitating their import into the peroxisome. The encoded protein is also capable of removing the C-terminal peroxisomal targeting signal (PTS1) from proteins in the peroxisomal matrix. The full-length protein undergoes self-cleavage to produce shorter, potentially inactive, peptides. Alternative splicing results in multiple transcript variants for this gene. [provided by RefSeq, Jan 2013]

Orthologs

SymbolSpecies
CG3589 Drosophila melanogaster
tysnd1 Danio rerio
Tysnd1 Mus musculus
Tysnd1 Rattus norvegicus

Links to external resources

Changes associated with this gene

GO Terms

GO IDGO TermGO Category
GO:0006508 proteolysis biological_process
GO:0016485 protein processing biological_process
GO:0031998 regulation of fatty acid beta-oxidation biological_process
GO:0051260 protein homooligomerization biological_process
GO:0005777 peroxisome cellular_component
GO:0002020 protease binding molecular_function
GO:0004252 serine-type endopeptidase activity molecular_function
GO:0008233 peptidase activity molecular_function
GO:0042802 identical protein binding molecular_function