death-associated protein
Symbol
DAP
(may also be known as: None)
Organism
Human
Description
This gene encodes a basic, proline-rich, 15-kD protein. The protein acts as a positive mediator of programmed cell death that is induced by interferon-gamma. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014]
Orthologs
| Symbol | Species | |
|---|---|---|
| CG12384 | Drosophila melanogaster | |
| dap | Danio rerio | |
| Dap | Mus musculus | |
| Dap | Rattus norvegicus |
Links to external resources
Changes associated with this gene
GO Terms
| GO ID | GO Term | GO Category | |
|---|---|---|---|
| GO:0006915 | apoptotic process | biological_process | |
| GO:0006919 | activation of caspase activity | biological_process | |
| GO:0008624 | induction of apoptosis by extracellular signals | biological_process | |
| GO:0010507 | negative regulation of autophagy | biological_process | |
| GO:0032088 | negative regulation of NF-kappaB transcription factor activity | biological_process | |
| GO:0034198 | cellular response to amino acid starvation | biological_process | |
| GO:0045892 | negative regulation of transcription, DNA-dependent | biological_process | |
| GO:0070513 | death domain binding | molecular_function | |