sphingosine-1-phosphate phosphatase 2
Symbol
SGPP2
(may also be known as: None)
Organism
Human
Description
Sphingosine-1-phosphate (S1P) is a bioactive sphingolipid metabolite that regulates diverse biologic processes. SGPP2 catalyzes the degradation of S1P (Ogawa et al., 2003 [PubMed 12411432]).[supplied by OMIM, Jun 2009]
Orthologs
| Symbol | Species | |
|---|---|---|
| LOC100330698 | Danio rerio | |
| Sgpp2 | Mus musculus | |
| Sgpp2 | Rattus norvegicus | |
| YSR3 | Saccharomyces cerevisiae |
Links to external resources
Changes associated with this gene
GO Terms
| GO ID | GO Term | GO Category | |
|---|---|---|---|
| GO:0006665 | sphingolipid metabolic process | biological_process | |
| GO:0006670 | sphingosine metabolic process | biological_process | |
| GO:0030148 | sphingolipid biosynthetic process | biological_process | |
| GO:0044281 | small molecule metabolic process | biological_process | |
| GO:0005783 | endoplasmic reticulum | cellular_component | |
| GO:0005789 | endoplasmic reticulum membrane | cellular_component | |
| GO:0016020 | membrane | cellular_component | |
| GO:0016021 | integral to membrane | cellular_component | |
| GO:0016787 | hydrolase activity | molecular_function | |
| GO:0042392 | sphingosine-1-phosphate phosphatase activity | molecular_function | |