phosphatase and actin regulator 3
Symbol
PHACTR3
(may also be known as: None)
Organism
Human
Description
This gene encodes a member of the phosphatase and actin regulator protein family. The encoded protein is associated with the nuclear scaffold in proliferating cells, and binds to actin and the catalytic subunit of protein phosphatase-1, suggesting that it functions as a regulatory subunit of protein phosphatase-1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
Orthologs
| Symbol | Species | |
|---|---|---|
| CG32264 | Drosophila melanogaster | |
| phactr3b | Danio rerio | |
| Phactr3 | Mus musculus | |
| Phactr3 | Rattus norvegicus |
Links to external resources
Changes associated with this gene
| Identifier | Name | Type | Tissues | Organism | Gene | Data | Actions |
|---|---|---|---|---|---|---|---|
| DAA2945 | Gene expression of PHACTR3 increases with age | Molecular | adipose tissue | Human | PHACTR3 | — |
GO Terms
| GO ID | GO Term | GO Category |
|---|---|---|
| GO:0005634 | nucleus | cellular_component |
| GO:0016363 | nuclear matrix | cellular_component |
| GO:0003779 | actin binding | molecular_function |
| GO:0004864 | protein phosphatase inhibitor activity | molecular_function |