cholinergic receptor, nicotinic, epsilon (muscle)

Symbol

CHRNE (may also be known as: None)

Organism

Human

Description

Acetylcholine receptors at mature mammalian neuromuscular junctions are pentameric protein complexes composed of four subunits in the ratio of two alpha subunits to one beta, one epsilon, and one delta subunit. The acetylcholine receptor changes subunit composition shortly after birth when the epsilon subunit replaces the gamma subunit seen in embryonic receptors. Mutations in the epsilon subunit are associated with congenital myasthenic syndrome. [provided by RefSeq, Sep 2009]

Orthologs

SymbolSpecies
chrne Danio rerio
Chrne Mus musculus
Chrne Rattus norvegicus

Links to external resources

Changes associated with this gene

GO Terms

GO IDGO TermGO Category
GO:0006810 transport biological_process
GO:0006812 cation transport biological_process
GO:0006936 muscle contraction biological_process
GO:0007165 signal transduction biological_process
GO:0007268 synaptic transmission biological_process
GO:0007271 synaptic transmission, cholinergic biological_process
Show more GO terms