fibrinogen-like 2
Symbol
FGL2
(may also be known as: None)
Organism
Human
Description
The protein encoded by this gene is a secreted protein that is similar to the beta- and gamma-chains of fibrinogen. The carboxyl-terminus of the encoded protein consists of the fibrinogen-related domains (FRED). The encoded protein forms a tetrameric complex which is stabilized by interchain disulfide bonds. This protein may play a role in physiologic functions at mucosal sites. [provided by RefSeq, Jul 2008]
Orthologs
| Symbol | Species | |
|---|---|---|
| fgl2 | Danio rerio | |
| Fgl2 | Mus musculus | |
| Fgl2 | Rattus norvegicus |
Links to external resources
Changes associated with this gene
| Identifier | Name | Type | Tissues | Organism | Gene | Data | Actions |
|---|---|---|---|---|---|---|---|
| DAA3650 | Gene expression of FGL2 decreases with age | Molecular | skin | Human | FGL2 | — | |
| DAA2872 | Gene expression of FGL2 decreases with age | Molecular | adipose tissue | Human | FGL2 | — |
GO Terms
| GO ID | GO Term | GO Category |
|---|---|---|
| GO:0007165 | signal transduction | biological_process |
| GO:0005576 | extracellular region | cellular_component |
| GO:0005577 | fibrinogen complex | cellular_component |
| GO:0005102 | receptor binding | molecular_function |