ATP-binding cassette, sub-family A (ABC1), member 8


ABCA8 (may also be known as: None)




The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. The function of this protein has not yet been determined. [provided by RefSeq, Jul 2008]


Abca8b Mus musculus
Abca8 Rattus norvegicus

Links to external resources

Changes associated with this gene

Identifier Name Type Tissues Organism Gene Data Actions
DAA2393 ATP-binding cassette; sub-family A member 8 decreases with age Molecular dermis Human ABCA8 23.4% Decrease DNA Methylation
DAA2442 ATP-binding cassette; sub-family A member 8 decreases with age Molecular mesenchymal stem cell Human ABCA8 25.0% Decrease DNA Methylation

GO Terms

GO IDGO TermGO Category
GO:0006810 transport biological_process
GO:0055085 transmembrane transport biological_process
GO:0005743 mitochondrial inner membrane cellular_component
GO:0005886 plasma membrane cellular_component
GO:0016021 integral to membrane cellular_component
GO:0000166 nucleotide binding molecular_function
GO:0005524 ATP binding molecular_function
GO:0016887 ATPase activity molecular_function
GO:0042626 ATPase activity, coupled to transmembrane movement of substances molecular_function