TRK-fused gene

Symbol

TFG (may also be known as: None)

Organism

Human

Description

There are several documented fusion oncoproteins encoded partially by this gene. This gene also participates in several oncogenic rearrangements resulting in anaplastic lymphoma and mixoid chondrosarcoma, and may play a role in the NF-kappaB pathway. Multiple transcript variants have been found for this gene. [provided by RefSeq, Sep 2010]

Orthologs

SymbolSpecies
tfg-1 Caenorhabditis elegans
tfg Danio rerio
Tfg Mus musculus
Tfg Rattus norvegicus

Links to external resources

Changes associated with this gene

Identifier Name Type Tissues Organism Gene Data Actions
DAA2637 Hypomethylation of TFG is positively correlated with age Molecular blood Human TFG —

GO Terms

GO IDGO TermGO Category
GO:0007165 signal transduction biological_process
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB cascade biological_process
GO:0005737 cytoplasm cellular_component
GO:0004871 signal transducer activity molecular_function
GO:0005515 protein binding molecular_function
GO:0042802 identical protein binding molecular_function