amyloid beta (A4) precursor protein-binding, family B, member 3
Symbol
APBB3
(may also be known as: None)
Organism
Human
Description
The protein encoded by this gene is a member of the APBB protein family. It is found in the cytoplasm and binds to the intracellular domain of the Alzheimer's disease beta-amyloid precursor protein (APP) as well as to other APP-like proteins. It is thought that the protein encoded by this gene may modulate the internalization of APP. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Orthologs
| Symbol | Species | |
|---|---|---|
| feh-1 | Caenorhabditis elegans | |
| uncharacterized_E7FF | Danio rerio | |
| Apbb3 | Mus musculus | |
| Apbb3 | Rattus norvegicus |
Links to external resources
Changes associated with this gene
GO Terms
| GO ID | GO Term | GO Category |
|---|---|---|
| GO:0005737 | cytoplasm | cellular_component |
| GO:0015629 | actin cytoskeleton | cellular_component |
| GO:0001540 | beta-amyloid binding | molecular_function |