Weiskopf et al. (2009) "The aging of the immune system." Transpl. Int. 22(11):1041-1050 (PubMed) (28 entries)

Changes associated with this reference

Identifier Name Type Tissues Organism Gene Data Actions
DAA991 Decreased function of epithelial barriers Physiological lung, oral cavity, pharynx, oesophagus, stomach, intestine, epidermis Human
DAA934 Number of mature B cells leaving the bone marrow declines Physiological bone marrow, B cell Human
DAA935 Pro-B cell generation and differentiation declines Physiological bone marrow, B cell Human
DAA932 Renewal capacity declines Physiological hematopoietic stem cells Human
DAA968 Chronic inflammation increases Physiological blood, immune system Human
DAA933 No changes in erythroid and myeloid progenitor cells evident Physiological myeloid progenitor cell Human
DAA991 Decreased function of epithelial barriers Physiological lung, oral cavity, pharynx, oesophagus, stomach, intestine, epidermis Human
DAA991 Decreased function of epithelial barriers Physiological lung, oral cavity, pharynx, oesophagus, stomach, intestine, epidermis Human
DAA991 Decreased function of epithelial barriers Physiological lung, oral cavity, pharynx, oesophagus, stomach, intestine, epidermis Human
DAA991 Decreased function of epithelial barriers Physiological lung, oral cavity, pharynx, oesophagus, stomach, intestine, epidermis Human
DAA991 Decreased function of epithelial barriers Physiological lung, oral cavity, pharynx, oesophagus, stomach, intestine, epidermis Human
DAA991 Decreased function of epithelial barriers Physiological lung, oral cavity, pharynx, oesophagus, stomach, intestine, epidermis Human
DAA960 Receptor expression alterations Physiological grey matter Human
DAA950 Immune response to Epstein-Barr virus decreases in cytomegalovirus positive individuals Physiological immune system Human
DAA949 Cytomegalovirus infection incidence increases Pathological immune system Human
DAA968 Chronic inflammation increases Physiological blood, immune system Human
DAA966 Vaccination antibody response is impaired Physiological immune system Human
DAA948 Volume of perivascular space around thymus increases Physiological thymus Human
DAA1229 Declining T-lymphocyte production in the thymus Physiological thymus Human
DAA945 Thymus involution Physiological thymus Human
DAA934 Number of mature B cells leaving the bone marrow declines Physiological bone marrow, B cell Human
DAA943 Lower affinity antibodies generated Physiological B cell Mouse
DAA939 Naive cell number increases and memory cells decrease Physiological B cell Human
DAA935 Pro-B cell generation and differentiation declines Physiological bone marrow, B cell Human
DAA940 B naive cells' susceptibility to apoptosis decreases Physiological memory B cell Human