All changes for the tissue brain (53)

Identifier Name Type Tissues Organism Gene Data Actions
DAA1948 Neurogenesis is reduced Physiological brain Mouse
DAA2036 Neural stem cell pool declines Physiological hippocampus Mouse
DAA1949 Intracellular glutathione content decreases Physiological brain Mouse
DAA2037 Decrease in mitochondrial content and oxidative metabolism in cells Physiological brain Mouse
DAA730 White matter volume decreases Physiological white matter Human
DAA788 Viscoelastic modulus of brain tissue decreases Physiological brain Human
DAA718 Synaptic density slightly decreases at advanced ages Physiological frontal lobe Human
DAA743 Sensitivity of HPA axis is impaired Physiological pituitary gland, adrenal gland, hypothalamus Human
DAA1981 Selective increase in oxidative damage and decrease in antioxidant function during aging in the substantia nigra Physiological substantia nigra Human
DAA785 Reduced hippocampal activity and functional connectivity in tests for verbal familiarity Physiological brain Human
DAA960 Receptor expression alterations Physiological grey matter Human
DAA1980 Reaction time for a visually paced simple motor task increases with age Physiological brain Human
DAA763 Prolongation of calcium signals in nerve cells Physiological brain Human
DAA779 Prefrontal cortex activation during learning is reduced Physiological brain Human
DAA737 Permeability increases with age Physiological blood brain barrier Human
DAA733 Neurotransmitter and neuro receptor concentrations are altered Physiological brain Human
DAA714 Neuronal soma shrinks in size Physiological brain Human
DAA721 Neurofibrillary tangles and Lewy bodies in neurons Physiological brain Human
DAA2026 Mutations in mitochondrial DNA accumulate Physiological heart, kidney, skeletal muscle, cerebral cortex, cerebellum Human
DAA2026 Mutations in mitochondrial DNA accumulate Physiological heart, kidney, skeletal muscle, cerebral cortex, cerebellum Human
DAA780 Medial temporal activation during encoding and retrieval of memory is reduced Physiological brain Human
DAA731 Mean diffusivity increases and water diffusion anisotropy decreases Physiological corpus callosum, white matter Human
DAA731 Mean diffusivity increases and water diffusion anisotropy decreases Physiological corpus callosum, white matter Human
DAA735 Localized increases and decreases in synaptic transmission Physiological brain Human
DAA725 Leukoaraiosis Physiological white matter Human