| DAA977 |
ROS production in response to stimuli unchanged |
— |
neutrophil |
Human |
|
| DAA979 |
Apoptotic pathway in response to stimuli disrupted |
— |
neutrophil |
Human |
|
| DAA980 |
Phagocytosis activity decreased in response to opsonized targets |
— |
neutrophil |
Human |
|
| DAA981 |
Phagocytosis activity unchanged in response to unopsonized targets |
— |
neutrophil |
Human |
|
| DAA983 |
Diminished superoxide production in response to Fc |
— |
neutrophil |
Human |
|
| DAA984 |
Spontaneous production of superoxide decreased |
— |
neutrophil |
Human |
|
| DAA985 |
Functional decline and decreases in macrophage numbers in bone marrow |
— |
macrophage |
Human |
|
| DAA986 |
Cytotoxicity and interleukin-2 response of natural killer cells decreases |
— |
natural killer cell |
Human |
|
| DAA987 |
Increase in total number of cells |
— |
natural killer cell |
Human |
|
| DAA991 |
Decreased function of epithelial barriers |
— |
lung, oral cavity, pharynx, oesophagus, stomach, intestine, epidermis |
Human |
|
| DAA992 |
Decrease in dermal papillae density |
— |
epidermis, dermis |
Human |
|
| DAA993 |
Epidermis held less tightly to dermis |
— |
epidermis |
Human |
|
| DAA994 |
Skin thinning |
— |
epidermis, dermis |
Human |
|
| DAA995 |
Change in weave of dermis collagen fibers |
— |
dermis |
Human |
|
| DAA996 |
Changes to dermis collagen fiber bundles |
— |
dermis |
Human |
|
| DAA997 |
Elastin fibers lost from upper layers of dermis |
— |
dermis |
Human |
|
| DAA998 |
Changes to elastin fibers in lower dermis |
— |
dermis |
Human |
|
| DAA999 |
Microvascular alterations in arterioles, capillaries, and venules in dermis/hypodermis |
— |
dermis, subcutaneous |
Human |
|