transcription factor 4

Symbol

TCF4 (may also be known as: E2-2 ITF2 )

Organism

Human

Orthologs

SymbolSpecies
Tcf4 Mus musculus
Tcf4 Rattus norvegicus

Links to external resources

Changes associated with this gene

Identifier Name Type Tissues Organism Gene Data Actions
DAA1201 TCF4 exon 1 methylation increases Molecular gastric mucosa Human TCF4 Increase DNA Methylation

GO Terms

GO IDGO TermGO Category
GO:0000122 negative regulation of transcription from RNA polymerase II promoter biological_process
GO:0006352 transcription initiation, DNA-dependent biological_process
GO:0006355 regulation of transcription, DNA-dependent biological_process
GO:0006367 transcription initiation from RNA polymerase II promoter biological_process
GO:0007399 nervous system development biological_process
GO:0030154 cell differentiation biological_process
GO:0045666 positive regulation of neuron differentiation biological_process
GO:0045893 positive regulation of transcription, DNA-dependent biological_process
GO:0045944 positive regulation of transcription from RNA polymerase II promoter biological_process
GO:0065004 protein-DNA complex assembly biological_process
GO:0005634 nucleus cellular_component
GO:0005667 transcription factor complex cellular_component
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding molecular_function
GO:0001011 sequence-specific DNA binding RNA polymerase recruiting transcription factor activity molecular_function
GO:0001077 RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription molecular_function
GO:0001087 TFIIB-class binding transcription factor activity molecular_function
GO:0001093 TFIIB-class transcription factor binding molecular_function
GO:0003677 DNA binding molecular_function
GO:0003700 sequence-specific DNA binding transcription factor activity molecular_function
GO:0003714 transcription corepressor activity molecular_function
GO:0005515 protein binding molecular_function
GO:0008022 protein C-terminus binding molecular_function
GO:0046982 protein heterodimerization activity molecular_function
GO:0070888 E-box binding molecular_function