solute carrier family 2 (facilitated glucose transporter), member 1

Symbol

SLC2A1

Organism

Human

Description

This gene encodes a major glucose transporter in the mammalian blood-brain barrier. Mutations in this gene have been found in a family with paroxysmal exertion-induced dyskinesia. [provided by RefSeq, Jul 2008]

Orthologs

SymbolSpecies
slc2a1a Danio rerio
Slc2a1 Mus musculus
Slc2a1 Rattus norvegicus

Links to external resources

Changes associated with this gene

Identifier Name Type Tissues Organism Gene Data Actions
DAA3395 Gene expression of SLC2A1 increases with age Molecular skin Human SLC2A1 —
DAA1066 glucose transporter 1 activity decreases Molecular blood brain barrier Human SLC2A1 —

Changes associated with the orthologs of this gene

Identifier Name Type Tissues Organism Gene Data Actions
DAA1438 solute carrier family 2 (facilitated glucose transporter), member 1 Molecular hippocampus Mouse Slc2a1 6.0% Increase Gene Expression Level

GO Terms

GO IDGO TermGO Category
GO:0005975 carbohydrate metabolic process biological_process
GO:0006112 energy reserve metabolic process biological_process
GO:0006766 vitamin metabolic process biological_process
GO:0006767 water-soluble vitamin metabolic process biological_process
GO:0006970 response to osmotic stress biological_process
GO:0008643 carbohydrate transport biological_process
GO:0008645 hexose transport biological_process
GO:0015758 glucose transport biological_process
GO:0019852 L-ascorbic acid metabolic process biological_process
GO:0035428 hexose transmembrane transport biological_process
GO:0042149 cellular response to glucose starvation biological_process
GO:0044281 small molecule metabolic process biological_process
GO:0050796 regulation of insulin secretion biological_process
GO:0055085 transmembrane transport biological_process
GO:0001939 female pronucleus cellular_component
GO:0005622 intracellular cellular_component
GO:0005624 membrane fraction cellular_component
GO:0005737 cytoplasm cellular_component
GO:0005886 plasma membrane cellular_component
GO:0005901 caveola cellular_component
GO:0005911 cell-cell junction cellular_component
GO:0016020 membrane cellular_component
GO:0016021 integral to membrane cellular_component
GO:0016323 basolateral plasma membrane cellular_component
GO:0030496 midbody cellular_component
GO:0031982 vesicle cellular_component
GO:0042470 melanosome cellular_component
GO:0005355 glucose transmembrane transporter activity molecular_function
GO:0019900 kinase binding molecular_function
GO:0022857 transmembrane transporter activity molecular_function
GO:0022891 substrate-specific transmembrane transporter activity molecular_function
GO:0033300 dehydroascorbic acid transporter activity molecular_function
GO:0042802 identical protein binding molecular_function
GO:0042910 xenobiotic transporter activity molecular_function
GO:0055056 D-glucose transmembrane transporter activity molecular_function