proteasome (prosome, macropain) 26S subunit, non-ATPase, 8

Symbol

PSMD8 (may also be known as: S14, Nin1p)

Organism

Human

Orthologs

SymbolSpecies
rpn-12 Caenorhabditis elegans
Rpn12 Drosophila melanogaster
psmd8 Danio rerio
Psmd8 Mus musculus
Psmd8 Rattus norvegicus
RPN12 Saccharomyces cerevisiae
rpn12 Schizosaccharomyces pombe

Links to external resources

Changes associated with this gene

Identifier Name Type Tissues Organism Gene Data Actions
DAA189 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 Molecular brain Human PSMD8 8.0% Decrease Gene Expression Level

GO Terms

GO IDGO TermGO Category
GO:0000075 cell cycle checkpoint biological_process
GO:0000082 G1/S transition of mitotic cell cycle biological_process
GO:0000084 S phase of mitotic cell cycle biological_process
GO:0000209 protein polyubiquitination biological_process
GO:0000216 M/G1 transition of mitotic cell cycle biological_process
GO:0000278 mitotic cell cycle biological_process
GO:0002474 antigen processing and presentation of peptide antigen via MHC class I biological_process
GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent biological_process
GO:0006508 proteolysis biological_process
GO:0006521 regulation of cellular amino acid metabolic process biological_process
GO:0006915 apoptotic process biological_process
GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest biological_process
GO:0010467 gene expression biological_process
GO:0016032 viral reproduction biological_process
GO:0016070 RNA metabolic process biological_process
GO:0016071 mRNA metabolic process biological_process
GO:0031145 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process biological_process
GO:0034641 cellular nitrogen compound metabolic process biological_process
GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I biological_process
GO:0042981 regulation of apoptotic process biological_process
GO:0044281 small molecule metabolic process biological_process
GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle biological_process
GO:0051437 positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle biological_process
GO:0051439 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle biological_process
GO:0000502 proteasome complex cellular_component
GO:0005634 nucleus cellular_component
GO:0005654 nucleoplasm cellular_component
GO:0005730 nucleolus cellular_component
GO:0005737 cytoplasm cellular_component
GO:0005829 cytosol cellular_component
GO:0005838 proteasome regulatory particle cellular_component