F-box and leucine-rich repeat protein 16
Symbol
FBXL16
(may also be known as: None)
Organism
Human
Description
Members of the F-box protein family, such as FBXL16, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008]
Orthologs
| Symbol | Species | |
|---|---|---|
| CG32085-RA | Drosophila melanogaster | |
| si:dkey-20j1.3 | Danio rerio | |
| Fbxl16 | Mus musculus | |
| Fbxl16 | Rattus norvegicus |